Process Research Director jobs in Colorado

Position Overview

The Umoja Biopharma Process Analytics team is seeking a driven Research Associate to conduct studies to support characterization of Lentiviral Vector (LVV). The successful candidate will be trained under the direction of senior staff to perform a variety of molecular, cellular, biophysical and biochemical protocols. This position works closely with other functions to develop LVV product- and process-related analytical methods and successfully transfer qualified methods to QC Analytical. This position plays a critical role in advancing Umoja's pipeline and Analytical Development capabilities.

This position will be based in Louisville, CO. Note: As early as September 2023 this role will work out of our new facility – the CLIMB – in Louisville, CO. The CLIMB is our Colorado Laboratory & Innovative Manufacturing Building and is located at 725 Tech Court Louisville, CO 80027.

Core Accountabilities

• Assist with method design, execution, and analysis to support the development of a gene therapy product
• Collaborate with Seattle team members to co-develop analytical methods, as well as participate in tech transfer of methods
• Perform routine impurity testing (e.g., ELISA, qPCR) to support Process Development
• Write Method Development Reports and qualification reports, as well as perform method qualification
• Transfer analytical methods to QC and provide SME support for method validation
• Maintain clear records of experimental work using an electronic notebook system that adheres to company guidelines
• Manage sample submissions in Benchling for assigned methods and turn around the data in timely manner
• Prepare technical data reports and presentations
• Communicate research and data in cross-functional meetings

Qualifications:

• A BS or MS in Biology, Biochemistry, or related discipline and 1-3 years of experience; equivalent combinations of education and experience will be considered.
• Hands-on experience with one or more of following techniques: ddPCR, qPCR, ELISA, and flow cytometry

Preferred Qualifications:

• Excellent communication skills with the proven ability to build open and collaborative relationships and work effectively as a member of a multidisciplinary team
• Experience with viral vectors (e.g., AAV, LVV) is a plus
• Self-motivation, organization, effective communication and presentation skills
• Ability to work in a fast-paced environment, meet deadlines, and prioritize work on multiple projects

Physical Requirements:

• 100% compliance with personal protective equipment (PPE) requirements in laboratory environments, including gloves, protective clothing, and eye safety glasses.
• Perform physical tasks required for the role, including standing, walking, bending, kneeling, sitting, working your hands in a biosafety cabinet, and occasionally moving materials up to 50 pounds.
• Project-oriented work in this role will require regular on-site presence to complete essential job-related functions for analytical development and execution.

Salary Range: $72,250 - $93,500